Fluid that collects in extracellular, extravascular spaces can be either exudative or transudative. Exudative fluid arises from inflammatory processes that make vessel walls more permeable to both fluid and proteins which allow them to exit the vessels and collect in the extravascular spaces. Transudative fluid exits the vessels due to a pressure differential between the intra and extravascular space (either hydrostatic or oncotic), but typically does not contain proteins since they are too large to squeeze out of the vessels. A fluid sample can be tested according to Light’s criteria to determine if it is exudative or transudative.
Exudates are from Enflammation (inflammation)
Light’s criteria – protein 5, LDH 6
(fluid protein:serum protein >0.5, fluid LDH:serum LDH>0.6) Continue reading “Exudate VS Transudate”